Dosage form characteristics of microsphere-in-oil emulsions. I. Stability and drug release.

Thermodynamic Stability of Water-in-oil Emulsions

It is well known that colloids can show phase transitions similar to the ones observed in molecular systems. Colloid-diluted and colloid-concentrated phases can coexist in thermodynamic equilibrium at certain conditions. In a previous work, the authors of this research have used this concept to study petroleum emulsions stability, applying thermodynamic perturbation theories to calculate a phas...

Physicochemical evaluation, study of stability and drug release kinetics from

Introduction: Acne is a disorder of the pilosebaceous unit of the skin and can present as non inflammatory and or inflammatory lesions. Tretinoin has been used therapeutically for over three decades. It is best known for its comedolytic effects on acne. It also inhibits comedone rupture, thus decreasing inflammatory events. Tretinoin is available in 0.01% to 0.1% as cream, gel or lotion. The ...

Crude Oil Emulsions – Composition Stability and Characterization

Interfacial interactions and the stability of oil-in- water emulsions

Various aspects of the formation and stability of oil-in-water emulsions are described. small-molecule surfactants are considered, and influences of interfacial interactions and competitive adsorption are discussed. Differences between adsorbed layers of proteins and

Development and Evaluation of Thymol Microparticles Using Cellulose Derivatives as Controlled Release Dosage Form

Thymol, an important and advantageous component of many essential oils, has been applied as an antimicrobial agent in animals. To increase the duration of action of this compound in ruminants, it was decided here to prepare a controlled release carrier for thymol. Hydroxy propyl methyl cellulose (HPMC) and ethyl cellulose (EC) were used as the matrix polymer here. Mixtures of thymol with eight ...